Intact Mass and Cell Culture Media Workflows
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Published by
Waters Corporation
Version 2, 17 Oct 2024 at 6:54 AM
These protocols enables upstream engineers to routinely collect product quality attributes and metabolite information for monitoring and as part of the Waters Bioprocess Walk-Up Solutions.
With the OneLab waters_connect integration, Waters provides a streamlined and user-friendly process for performing precise and accurate sample preparation using the Andrew+ Pipetting Robot directly followed by high-quality LC-MS data acquired using the BioAccord System.
Get in touch with an expert about running this protocol on Andrew+.
Please note that this is a “Click & Execute Method”
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Protocols
3
Intact Mass and CCM Protocol with Clarification
Sample Preparation with LCMS for intact mass and CCM with filtration and pre-dilution
Intact Mass and CCM Protocol with Sealing
Sample Preparation with LCMS for intact mass and CCM (automated sealing)
ProA Mag bead purification for 8 media samples in PCR plate
Purification of antibody from conditioned cell culture media (8 samples) using Promega Magne® Protein A Beads on the Andrew+ Pipetting Robot.
With sealing and LCMS analysis steps.
Contact info
Published by
Waters Corporation
From the everyday consumer to scientists in the laboratory, we all rely on accurate information to make critical decisions. Waters Corporation is the world's leading specialty measurement company focused on improving human health and well-being through the application of high-value analytical technologies and industry leading scientific expertise.
This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 