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Automated NucleoBond Xtra Midiprep
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.

Published by
MACHEREY-NAGEL
Version 6, 19 Aug 2026 at 4:49 PM
With our long-standing experience in chromatography and nucleic acid purification, MACHEREY-NAGEL is an ideal choice for high-quality plasmid preps.
Together with Andrew Alliance, we have developed the hardware and protocols for easy automation of up to 6 plasmid midi preps in parallel, providing you with a reliable solution for plasmid purification without the tedious work of manually processing samples.
Get in touch with an expert about running this protocol on Andrew+.
Please note that this is a “Click & Execute Method”
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Overview
Protocols
5

Automated NucleoBond Xtra Midiprep, 3 Samples
Purification of transfection-grade plasmid DNA isolation from 3 samples on the Andrew+ Pipetting Robot using MACHEREY-NAGEL NucleoBond® Xtra Midi kit, including a magnetic-bead-based desalting step.

Automated NucleoBond Xtra Midiprep, 3 Samples, Filter Tips
Purification of transfection-grade plasmid DNA isolation from 3 samples on the Andrew+ Pipetting Robot (with filter tips) using MACHEREY-NAGEL NucleoBond® Xtra Midi kit, including a magnetic-bead-based desalting step.

Automated NucleoBond Xtra Midiprep, 6 Samples
Purification of transfection-grade plasmid DNA isolation from 6 samples on the Andrew+ Pipetting Robot using MACHEREY-NAGEL NucleoBond® Xtra Midi kit, including a magnetic-bead-based desalting step.

Automated NucleoBond Xtra Midiprep, 6 Samples, Filter Tips
Purification of transfection-grade plasmid DNA isolation from 6 samples on the Andrew+ Pipetting Robot (with filter tips) using MACHEREY-NAGEL NucleoBond® Xtra Midi kit, including a magnetic-bead-based desalting step.

Automated NucleoBond Xtra Midiprep EF, 6 Samples
Purification of endotoxin-free (EF) plasmid DNA isolation from 6 samples on the Andrew+ Pipetting Robot using MACHEREY-NAGEL NucleoBond® Xtra Midi EF kit, including a magnetic-bead-based desalting step.
Contact info

Published by
MACHEREY-NAGEL
MACHEREY-NAGEL was founded in 1911 in Düren as a specialist manufacturer of filter papers. It has evolved into an innovative international company for chemical and biomolecular analysis. It has subsidiaries in Germany, Switzerland, France and the U.S. It has worldwide sales in 150 countries, and has more than 25,000 products in application areas that include water filtration, rapid test, analysis, chromatography, and bioanalysis tools, including DNA and RNA purification products.
This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 