Automated High-Throughput RNA Purification with NucleoSpin® 96 RNA and Andrew+
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Published by
MACHEREY-NAGEL
Version 1, 19 Aug 2026 at 4:49 PM
High-throughput RNA purification is a common bottleneck in transcriptomics and molecular biology workflows. The silica membrane-based NucleoSpin® 96 RNA kit, run on the Andrew+ robot with the Extraction+ vacuum module, automates purification of 8–96 samples in parallel with on-column DNase treatment, eliminating repetitive pipetting and manual vacuum steps. It delivers high-integrity RNA (RIN up to 10) with typical yields of 10–40 µg from cells and tissue, reducing errors and streamlining downstream analysis.
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Please note that this is a “Click & Execute Method”
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Protocols
1
NucleoSpin 96 RNA
Contact info
Published by
MACHEREY-NAGEL
MACHEREY-NAGEL was founded in 1911 in Düren as a specialist manufacturer of filter papers. It has evolved into an innovative international company for chemical and biomolecular analysis. It has subsidiaries in Germany, Switzerland, France and the U.S. It has worldwide sales in 150 countries, and has more than 25,000 products in application areas that include water filtration, rapid test, analysis, chromatography, and bioanalysis tools, including DNA and RNA purification products.
This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 