Automated High-Throughput PCR Clean-up with NucleoSpin® 96 PCR Clean-up and Andrew+
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Published by
MACHEREY-NAGEL
Version 1, 19 Aug 2026 at 4:49 PM
PCR clean-up is a time-consuming, error-prone step that limits throughput in cloning and sequencing workflows, especially when many samples must be processed at once. Automating the silica membrane-based NucleoSpin® 96 PCR Clean-up kit with the Andrew+ robot and Extraction+ vacuum module addresses this by handling 8–96 samples in parallel without manual pipetting or vacuum steps. The kit recovers 75–95 % of DNA fragments from PCRs and enzymatic reactions, delivering clean DNA ready for cloning and sequencing.
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Please note that this is a “Click & Execute Method”
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Protocols
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NucleoSpin 96 PCR Clean-up
Contact info
Published by
MACHEREY-NAGEL
MACHEREY-NAGEL was founded in 1911 in Düren as a specialist manufacturer of filter papers. It has evolved into an innovative international company for chemical and biomolecular analysis. It has subsidiaries in Germany, Switzerland, France and the U.S. It has worldwide sales in 150 countries, and has more than 25,000 products in application areas that include water filtration, rapid test, analysis, chromatography, and bioanalysis tools, including DNA and RNA purification products.
This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 