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Aura Membrane Plate Automated Preparation for Subvisible Particle Analysis
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.

Published by
Waters Corporation
Version 1, 19 Aug 2026 at 4:49 PM
Backgrounded Membrane Imaging (BMI) and Fluorescence Membrane Microscopy (FMM) detect subvisible particles in biotherapeutics. The Aura® membrane plate supports these analyses, while Andrew+™ with Extraction+ automates filling, mixing, loading, vacuuming, and washing ; reducing operator variance and achieving counts comparable to expert analysts with up to 3 times lower CV on samples like BSA.
Get in touch with an expert about running this protocol on Andrew+.
Please note that this is a “Click & Execute Method”
This advanced method offers an end-to-end solution developed around an advanced application, a specialized kit, or an analytical system. It delivers complete functional, ready-to-use protocols that are qualitatively and quantitatively assessed for consistency, executability, and repeatability, usually without needing to make any changes. It operates per batch size and is scalable to accommodate changing requirements.
Overview
Protocols
2

Aura Full Plate with Washes
Loading for Test Protocol for Aura PM
Using Repetitive mode
Using Aura+ 96x membrane labware

Aura Full Plate Fluorescent Protocol with Wash
Loading Protocol for Aura FL
Using repetitive mode
Using Aura+ 96x membrane labware
Contact info

Published by
Waters Corporation
From the everyday consumer to scientists in the laboratory, we all rely on accurate information to make critical decisions. Waters Corporation is the world's leading specialty measurement company focused on improving human health and well-being through the application of high-value analytical technologies and industry leading scientific expertise.
This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 